×
Entrez Id:
391356
Gene Symbol:
PTRHD1
PTRHD1
0.320
Biomarker
group
GENOMICS_ENGLAND
PTRHD1 and possibly ADORA1 mutations contribute to Parkinsonism with intellectual disability.
29143421
2018
×
Entrez Id:
1130
Gene Symbol:
LYST
LYST
0.300
Biomarker
group
GENOMICS_ENGLAND
Chediak-Higashi syndrome presenting as young-onset levodopa-responsive parkinsonism.
23436631
2013
×
Entrez Id:
1130
Gene Symbol:
LYST
LYST
0.300
Biomarker
group
GENOMICS_ENGLAND
Apparent genotype-phenotype correlation in childhood, adolescent, and adult Chediak-Higashi syndrome.
11857544
2002
×
Entrez Id:
1130
Gene Symbol:
LYST
LYST
0.300
Biomarker
group
GENOMICS_ENGLAND
[Clinical aspects of hereditary spastic paraplegias].
25519961
2014
×
Entrez Id:
65018
Gene Symbol:
PINK1
PINK1
0.700
Biomarker
group
RGD
Phenotypic characterization of recessive gene knockout rat models of Parkinson's disease.
24969022
2014
×
Entrez Id:
7054
Gene Symbol:
TH
TH
0.700
Biomarker
group
RGD
Decreased RGS9 protein level in the striatum of rodents undergoing MPTP or 6-OHDA neurotoxicity.
20561938
2010
×
Entrez Id:
4137
Gene Symbol:
MAPT
MAPT
0.700
Therapeutic
group
RGD
Human Basic Fibroblast Growth Factor Inhibits Tau Phosphorylation via the PI3K/Akt-GSK3β Signaling Pathway in a 6-Hydroxydopamine-Induced Model of Parkinson's Disease.
27228974
2016
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.600
Biomarker
group
RGD
Phenotypic characterization of recessive gene knockout rat models of Parkinson's disease.
24969022
2014
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.600
Therapeutic
group
RGD
Protection against dopaminergic neurodegeneration in Parkinson's disease-model animals by a modulator of the oxidized form of DJ-1, a wild-type of familial Parkinson's disease-linked PARK7.
22041943
2011
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.600
Therapeutic
group
RGD
DJ-1-binding compounds prevent oxidative stress-induced cell death and movement defect in Parkinson's disease model rats.
18373560
2008
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.600
Biomarker
group
RGD
Rotenone-induced parkinsonism elicits behavioral impairments and differential expression of parkin, heat shock proteins and caspases in the rat.
22710069
2012
×
Entrez Id:
2668
Gene Symbol:
GDNF
GDNF
0.530
Biomarker
group
RGD
Mildronate as a regulator of protein expression in a rat model of Parkinson's disease.
22186119
2011
×
Entrez Id:
2668
Gene Symbol:
GDNF
GDNF
0.530
Biomarker
group
RGD
Signaling of glial cell line-derived neurotrophic factor and its receptor GFRα1 induce Nurr1 and Pitx3 to promote survival of grafted midbrain-derived neural stem cells in a rat model of Parkinson disease.
21865882
2011
×
Entrez Id:
2936
Gene Symbol:
GSR
GSR
0.500
Therapeutic
group
RGD
Neuroprotective effects of curcumin on 6-hydroxydopamine-induced Parkinsonism in rats: behavioral, neurochemical and immunohistochemical studies.
20951685
2011
×
Entrez Id:
1813
Gene Symbol:
DRD2
DRD2
0.500
Biomarker
group
RGD
[Effect of Bushen Huoxue Decoction on dopamine D2 receptor in the brain of rats with Parkinson's disease].
22126770
2011
×
Entrez Id:
6531
Gene Symbol:
SLC6A3
SLC6A3
0.400
Biomarker
group
RGD
Grafts of adult subependymal zone neuronal progenitor cells rescue hemiparkinsonian behavioral decline.
15680936
2005
×
Entrez Id:
1437
Gene Symbol:
CSF2
CSF2
0.240
Biomarker
group
RGD
Therapeutic efficacy of intranasally delivered mesenchymal stem cells in a rat model of Parkinson disease.
21291297
2011
×
Entrez Id:
1312
Gene Symbol:
COMT
COMT
0.220
Biomarker
group
RGD
Early administration of entacapone prevents levodopa-induced motor fluctuations in hemiparkinsonian rats.
15698633
2005
×
Entrez Id:
3162
Gene Symbol:
HMOX1
HMOX1
0.220
Therapeutic
group
RGD
The systemic administration of oleoylethanolamide exerts neuroprotection of the nigrostriatal system in experimental Parkinsonism.
24169105
2014
×
Entrez Id:
836
Gene Symbol:
CASP3
CASP3
0.210
Therapeutic
group
RGD
Repetitive transcranial magnetic stimulation for treatment of lactacystin-induced Parkinsonian rat model.
28881616
2017
×
Entrez Id:
4891
Gene Symbol:
SLC11A2
SLC11A2
0.210
Biomarker
group
RGD
Up-regulation of divalent metal transporter 1 in 6-hydroxydopamine intoxication is IRE/IRP dependent.
20125122
2010
×
Entrez Id:
5979
Gene Symbol:
RET
RET
0.210
Biomarker
group
RGD
Regulation of c-Ret, GFRalpha1, and GFRalpha2 in the substantia nigra pars compacta in a rat model of Parkinson's disease.
12210101
2002
×
Entrez Id:
4891
Gene Symbol:
SLC11A2
SLC11A2
0.210
Biomarker
group
RGD
In addition, we report that a mutation in DMT1 that impairs iron transport protects rodents against parkinsonism -inducing neurotoxins MPTP and 6-hydroxydopamine.
19011085
2008
×
Entrez Id:
5743
Gene Symbol:
PTGS2
PTGS2
0.210
Biomarker
group
RGD
Different parkinsonism models produce a time-dependent induction of COX-2 in the substantia nigra of rats.
16781689
2006
×
Entrez Id:
3313
Gene Symbol:
HSPA9
HSPA9
0.210
Biomarker
group
RGD
Mortalin inhibition in experimental Parkinson's disease.
21542017
2011